In structural engineering, a pre-engineered building (PEB) is designed by a PEB supplier or PEB manufacturer, to be fabricated using best suited inventory of raw materials available from all sources and manufacturing methods that can efficiently satisfy a wide range of structural and aesthetic design requirements. Within some geographic industry sectors these buildings are also called Pre-Engineered Metal Buildings (PEMB) or, as is becoming increasingly common due to the reduced amount of pre-engineering involved in custom computer-aided designs, simply Engineered Metal Buildings (EMB).

Historically, the primary framing structure of a pre-engineered building is an assembly of I-shaped members, often referred as I-beams. In pre-engineered buildings, the I beams used are usually formed by welding together steel plates to form the I section. The I beams are then field-assembled (e.g. bolted connections) to form the entire frame of the pre-engineered building. Some manufacturers taper the framing members (varying in web depth) according to the local loading effects. Larger plate dimensions are used in areas of higher load effects.

Other forms of primary framing can include trusses, mill sections rather than three-plate welded, castellated beams, etc. The choice of economic form can vary depending on factors such as local capabilities (e.g. manufacturing, transportation, construction) and variations in material vs. labour costs.

Typically, primary frames are 2D type frames (i.e. may be analyzed using two-dimensional techniques). Advances in computer-aided design technology, materials and manufacturing capabilities have assisted a growth in alternate forms of pre-engineered building such as the tension fabric building and more sophisticated analysis (e.g. three-dimensional) as is required by some building codes.

Cold formed Z- and C-shaped members may be used as secondary structural elements to fasten and support the external cladding.

Roll-formed profiled steel sheet, wood, tensioned fabric, precast concrete, masonry block, glass curtainwall or other materials may be used for the external cladding of the building.

In order to accurately design a pre-engineered building, engineers consider the clear span between bearing points, bay spacing, roof slope, live loads, dead loads, collateral loads, wind uplift, deflection criteria, internal crane system and maximum practical size and weight of fabricated members. Historically, pre-engineered building manufacturers have developed pre-calculated tables for different structural elements in order to allow designers to select the most efficient I beams size for their projects. However, the table selection procedures are becoming rare with the evolution in computer-aided custom designs.

While pre-engineered buildings can be adapted to suit a wide variety of structural applications, the greatest economy will be realized when utilising standard details. An efficiently designed pre-engineered building can be lighter than the conventional steel buildings by up to 30%. Lighter weight equates to less steel and a potential price savings in structural framework.